RESUMEN 6: BRAZILIAN PRIMARY RENAL TUMORS: CLINICAL AND PATHOLOGICAL REVIEW OF 137 CASES WITH EMPHASIS ON RENAL CORTICAL EPITHELIAL NEOPLASMS.

Sueli Suzigan*, Marcio El Ammar Müller**, Wilson de Souza Lima*, Carlos Benedito Menezes Verona**, Miguel Zerati Filho** Larpac Laboratory* and Institute of Urology and Nephrology (IUN)**, São José do Rio Preto, SP, Brazil

IV-CVHAP 2001 COMUNICACIÓN-E - 002

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Abstract

     In Brazilian papers related to primary renal tumors and specially those using the "1997 Rochester/Minnesota Renal Cell Carcinoma Classification", documentation about renal cortical epithelial neoplasms (RCEN) is scarce. This paper is meant to correlate clinical and pathological data on this classification. Between January 1978 and March 2000 Larpac Laboratory received 137 primary renal neoplasms for analysis and they were reviewed retrospectively. From these, 122 cases were followed up by IUN. The following primary renal neoplasms were diagnosed: Collecting Duct Carcinoma (CDC) (0.74%), Leiomyosarcoma (1.46%), Cystic Nephroma (1.46%), Sarcoma (1.46%), Unclassified Carcinoma (1.46%), Oncocytoma (2.19%), Angiomyolipoma (6.57%), Wilms' Tumor (8.03%), Transitional Cell Carcinoma (15.33%) and Renal Cell Carcinoma (RCC) (61.31%). In relation to non-RCEN tumors: Leiomyosarcoma was seen in the sixth and seventh decades of life, only in females and in left kidneys. Cystic Nephroma as well as Sarcoma were found only in right kidneys, but the first was seen in the first and fourth decades of life and in males and the last only in the seventh decade of life and in females. Angiomyolipoma occurred from the fourth to the seventh decades of life, in a higher incidence in females (77.78%) and in right kidneys (66.67%). Wilms' Tumor was found in the first and second decades of life, with a frequency of 63.64% in both females and right kidneys. Transitional Cell Carcinoma occurred from the fifth to the ninth decades of life, with no differences between the sexes, but with a slight prevalence (52.38%) in right kidneys. In relation to RCEN tumors: CDC occurred in the third decade of life, in a male and in the left kidney. Unclassified Carcinoma was seen in the sixth and eighth decades of life and only in males. Oncocytoma was found from the sixth to the eighth decades of life, with an occurrence rate of 66.67% both for females and left kidneys. RCC was detected from the second to the ninth decades of life, with a slight prevalence in males and in left kidneys. With regard to RCC no significant differences were found between microscopic patterns and age or between microscopic patterns and sex. However, the median tumor diameter on male sex was significantly greater than that on female Sex (Vp=0,036) The subtypes of RCC were: Chromophobe RCC (16.67%), Papillary RCC (22.62%) and Conventional RCC (60.71%). There were 12 patients with RCC who died of the disease: zero of Chromophobe type, one of Papillary type and 11 of Conventional type. The two first types of RCC gave a better prognosis than the last one.

Apartado: Uropatología
Palabras clave: Renal Cortical Epithelial Neoplasms; Kidney; Tumors; Pathology Neoplasias del Epitelio Cortical Renal, Riñón, Tumores, Patología
Fecha recepción: 04/09/2000


Estado Comité Científico: Aceptado
Fecha evaluación: 19/09/2000

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